| H01726 | |
| H番号 | H01726 |
| 名称 | 膜性増殖性糸球体腎炎 |
| 概要 | Membranoproliferative glomerulonephritis (MPGN) represents a pattern of glomerular injury, characterized by mesangial proliferation and expansion, lobularization of the glomerular tufts, and double contours. Classification of MPGN has been updated in the 2010s and is now categorized according to the immunofluorescence microscopy findings. MPGN is now recognized as follows: Immunocomplexes-associated MPGN with complement over activation; MPGN with intramembranous dense deposits; and C3 glomerulopathy. |
| カテゴリ | 免疫系疾患; 泌尿器系疾患 |
| ネットワーク | - |
| 病因遺伝子 | CFH [HSA:3075] [KO:K04004] CFHR5 [HSA:81494] [KO:K23817] DGKE [HSA:8526] [KO:K00901] |
| 病原体 | - |
| 環境要因 | - |
| 発癌物質 | - |
| 治療薬 | - |
| コメント | - |
| リンク | ICD-11: MF8Y ICD-10: N03 MeSH: D015432 OMIM: 609814 614809 615008 |
| 文献 | PMID:27356907 著者 Lionaki S, Gakiopoulou H, Boletis JN タイトル Understanding the complement-mediated glomerular diseases: focus on membranoproliferative glomerulonephritis and C3 glomerulopathies. 雑誌 APMIS 124:725-35 (2016) DOI:10.1111/apm.12566 PMID:27458560 著者 Salvadori M, Rosso G タイトル Reclassification of membranoproliferative glomerulonephritis: Identification of a new GN: C3GN. 雑誌 World J Nephrol 5:308-20 (2016) DOI:10.5527/wjn.v5.i4.308 PMID:26921911 著者 Floege J, Amann K タイトル Primary glomerulonephritides. 雑誌 Lancet 387:2036-48 (2016) DOI:10.1016/S0140-6736(16)00272-5 |