| H00338 | |
| H number | H00338 |
| Name | Pseudomembranous colitis |
| Description | Clostridium difficile is a gram-positive anaerobic bacillus that causes a broad spectrum of clinical symptoms ranging from mild diarrhea to severe pseudomembranous colitis. C. difficile can be transmitted by the fecal-oral route from person to person and instrument to patient. |
| Category | Bacterial infectious disease |
| Network | - |
| Gene | - |
| Pathogen | Clostridioides difficile [GN:cdf pdc cdc cdl] toxin A/B [KO:K11063] pore-forming toxin [KO:K06442 K11068] |
| Env factor | - |
| Carcinogen | - |
| Drug | Fidaxomicin [DR:D09394] Bezlotoxumab [DR:D10453] |
| Comment | - |
| Other DBs | ICD-11: 1A04 ICD-10: A04.7 MeSH: D004761 MedlinePlus: 000259 |
| Reference | PMID:21609252 AUTHORS Kachrimanidou M, Malisiovas N TITLE Clostridium difficile infection: a comprehensive review. JOURNAL Crit Rev Microbiol 37:178-87 (2011) DOI:10.3109/1040841X.2011.556598 PMID:17640189 AUTHORS Elliott B, Chang BJ, Golledge CL, Riley TV TITLE Clostridium difficile-associated diarrhoea. JOURNAL Intern Med J 37:561-8 (2007) DOI:10.1111/j.1445-5994.2007.01403.x PMID:15997485 AUTHORS Bouza E, Munoz P, Alonso R TITLE Clinical manifestations, treatment and control of infections caused by Clostridium difficile. JOURNAL Clin Microbiol Infect 11 Suppl 4:57-64 (2005) DOI:10.1111/j.1469-0691.2005.01165.x |