| SKIP000796 | |
| SKIP ID | SKIP000796 |
| Organism(En) | - |
| Organism(Ja) | - |
| Cell Type(En) | - |
| Cell Type(Ja) | - |
| Cell Tissue(En) | - |
| Cell Tissue(Ja) | - |
| Cell Origin | Diseased |
| Cell Name 1(En) | P2 |
| Cell Name 1(Ja) | P2 |
| Cell Name 2(En) | CiRA00069 |
| Cell Name 2(Ja) | CiRA00069 |
| Disease Name 1(Ja) | 脊髄性筋萎縮症Ⅰ型 |
| ICD Code 1 | G120 |
| Disease Name 1(En) | SPINAL MUSCULAR ATROPHY I; SMA1 |
| OMIM1 | 253300 |
| Disease Name 2(Ja) | - |
| ICD Code 2 | - |
| Disease Name 2(En) | - |
| OMIM 2 | - |
| Disease Name 3(Ja) | - |
| ICD Code 3 | - |
| Disease Name 3(En) | - |
| OMIM 3 | - |
| Age | 3 |
| Age Range | 0-9 |
| Sex | Male |
| Race(En) | - |
| Race(Ja) | - |
| Genetic Diagnosis | Yes |
| Not Detected | No |
| Description(En) | SMA patient(Coriell IDs GM03813 Fibroblast)-derived induced pluripotent stem cells (iPSCs) |
| Description(Ja) | 脊髄性筋萎縮症（Coriell GM03813）患者由来のiPS細胞 |
| Cell Morphology | human ES-like |
| Grade | Research Grade |
| Vector | Other |
| Transgene | OCT3/4, SOX2, KLF4, L-MYC, LIN28 and p53 shRNA |
| Adhesiveness | - |
| Feeder | Yes |
| Feeder Cell | SNL or MEF |
| Medium | embryonic stem cell medium (ReproCELL) |
| Genome Editing | - |
| CO2 | - |
| Mycoplasma | - |
| Detection of Contaminants Mycoplasma | - |
| Pluripotent Markers | Yes |
| Pluripotent Markers Assay | Immunocytochemical analysis |
| in vitro Differentiation | Yes |
| in vitro Differentiation Assay | - |
| in vivo Differentiation | Yes |
| in vivo Differentiation Assay | Teratoma formation assay |
| Other 1 Assay | Yes |
| Other 1 Assay Method | q-PCR |
| Other 2 Assay | - |
| Other 2 Assay Method | - |
| Other 3 Assay | - |
| Other 3 Assay Method | - |
| Karyotype | Yes |
| Karyotype Assay | - |
| Remaining Vector Detection | - |
| Remaining Vector Detection Assay | - |
| STR | - |
| HLA | - |
| Stem Cell Transcriptome analysis | - |
| Stem Cell Transcriptome analysis Assay | - |
| Author Name(En) | Megumu K. Saito |
| Author Name(Ja) | 齋藤 潤 |
| Author Organization(En) | Department of Clinical Application, Center for iPS Cell Research and Application (CiRA), Kyoto University |
| Author Organization(Ja) | 京都大学iPS細胞研究所 |
| Author Contact Email | msaito[at]cira[dot]kyoto-u[dot]ac[dot]jp |
| PI Organization(En) | - |
| PI Organization(Ja) | - |
| PI Name(En) | - |
| PI Name(Ja) | - |
| PI Contact Email | - |
| Availability | Information Only |
| Provider Organization(En) | Department of Clinical Application, Center for iPS Cell Research and Application (CiRA), Kyoto University |
| Provider Organization(Ja) | 京都大学iPS細胞研究所 |
| Provider Email | msaito[at]cira[dot]kyoto-u[dot]ac[dot]jp |
| Provider URL | http://www.cira.kyoto-u.ac.jp/nakahata/ |
| Ethical Statement(En) | - |
| Ethical Statement(Ja) | - |
| Terms of Use(En) | - |
| Terms of Use(Ja) | - |
| PubMed ID | 25801509 |
| DOI | 10.1016/j.stemcr.2015.02.010 |
| Title | Modeling the early phenotype at the neuromuscular junction of spinal muscular atrophy using patient-derived iPSCs. |
| Authors | Yoshida M, Kitaoka S, Egawa N, Yamane M, Ikeda R, Tsukita K, Amano N, Watanabe A, Morimoto M, Takahashi J, Hosoi H, Nakahata T, Inoue H, Saito MK |
| Journal | Stem Cell Reports |
| Year | 2015 |
| Volume | 4 |
| Issue | 4 |
| Pages | 561-8 |
| URL | http://www.ncbi.nlm.nih.gov/pubmed/25801509 |
| Free input | - |
| Note | - |