Organism(En) -
Organism(Ja) -
Cell Type(En) -
Cell Type(Ja) -
Cell Tissue(En) -
Cell Tissue(Ja) -
Cell Origin Diseased
Cell Name 1(En) P2
Cell Name 1(Ja) P2
Cell Name 2(En) CiRA00069
Cell Name 2(Ja) CiRA00069
Disease Name 1(Ja) 脊髄性筋萎縮症Ⅰ型
ICD Code 1 G120
OMIM1 253300
Disease Name 2(Ja) -
ICD Code 2 -
Disease Name 2(En) -
OMIM 2 -
Disease Name 3(Ja) -
ICD Code 3 -
Disease Name 3(En) -
OMIM 3 -
Age 3
Age Range 0-9
Sex Male
Race(En) -
Race(Ja) -
Genetic Diagnosis Yes
Not Detected No
Description(En) SMA patient(Coriell IDs GM03813 Fibroblast)-derived induced pluripotent stem cells (iPSCs)
Description(Ja) 脊髄性筋萎縮症(Coriell GM03813)患者由来のiPS細胞
Cell Morphology human ES-like
Grade Research Grade
Vector Other
Transgene OCT3/4, SOX2, KLF4, L-MYC, LIN28 and p53 shRNA
Adhesiveness -
Feeder Yes
Feeder Cell SNL or MEF
Medium embryonic stem cell medium (ReproCELL)
Genome Editing -
CO2 -
Mycoplasma -
Detection of Contaminants Mycoplasma -
Pluripotent Markers Yes
Pluripotent Markers Assay Immunocytochemical analysis
in vitro Differentiation Yes
in vitro Differentiation Assay -
in vivo Differentiation Yes
in vivo Differentiation Assay Teratoma formation assay
Other 1 Assay Yes
Other 1 Assay Method q-PCR
Other 2 Assay -
Other 2 Assay Method -
Other 3 Assay -
Other 3 Assay Method -
Karyotype Yes
Karyotype Assay -
Remaining Vector Detection -
Remaining Vector Detection Assay -
Stem Cell Transcriptome analysis -
Stem Cell Transcriptome analysis Assay -
Author Name(En) Megumu K. Saito
Author Name(Ja) 齋藤 潤
Author Organization(En) Department of Clinical Application, Center for iPS Cell Research and Application (CiRA), Kyoto University
Author Organization(Ja) 京都大学iPS細胞研究所
Author Contact Email msaito[at]cira[dot]kyoto-u[dot]ac[dot]jp
PI Organization(En) -
PI Organization(Ja) -
PI Name(En) -
PI Name(Ja) -
PI Contact Email -
Availability Information Only
Provider Organization(En) Department of Clinical Application, Center for iPS Cell Research and Application (CiRA), Kyoto University
Provider Organization(Ja) 京都大学iPS細胞研究所
Provider Email msaito[at]cira[dot]kyoto-u[dot]ac[dot]jp
Provider URL
Ethical Statement(En) -
Ethical Statement(Ja) -
Terms of Use(En) -
Terms of Use(Ja) -
PubMed ID 25801509
DOI 10.1016/j.stemcr.2015.02.010
Title Modeling the early phenotype at the neuromuscular junction of spinal muscular atrophy using patient-derived iPSCs.
Authors Yoshida M, Kitaoka S, Egawa N, Yamane M, Ikeda R, Tsukita K, Amano N, Watanabe A, Morimoto M, Takahashi J, Hosoi H, Nakahata T, Inoue H, Saito MK
Journal Stem Cell Reports
Year 2015
Volume 4
Issue 4
Pages 561-8
Free input -
Note -