| H00353 | |
| H number | H00353 |
| Name | Lyme borreliosis; Lyme disease |
| Description | Lyme borreliosis is the multisystem infectious disease caused by the tick-borne spirochetes Borrelia. Localized infection is typically manifested by erythema migrans skin lesions. A broad variety of peripheral nerve disorders (Lyme neuroborreliosis) can occur as well. Late Lyme borreliosis usually manifests as arthritis or the skin disorder known as acrodermatitis chronica atrophicans. |
| Category | Bacterial infectious disease |
| Network | - |
| Gene | - |
| Pathogen | Borrelia burgdorferi (Lyme disease) [GN:bbu bbz bbn bbj] Borrelia garinii [GN:bga bgb bgc] Borrelia afzelii [GN:baf bafz bafh bafe] Borrelia bissettii [GN:bbs] Borrelia mayonii [GN:bmay] |
| Env factor | - |
| Carcinogen | - |
| Drug | Doxycycline hyclate [DR:D02129] Cefuroxime axetil [DR:D00914] |
| Comment | Vector: Ixodes sp. (tick) |
| Other DBs | ICD-11: 1C1G ICD-10: A69.2 MeSH: D008193 MedlinePlus: 001319 |
| Reference | PMID:21903253 AUTHORS Stanek G, Wormser GP, Gray J, Strle F TITLE Lyme borreliosis. JOURNAL Lancet 379:461-73 (2012) DOI:10.1016/S0140-6736(11)60103-7 PMID:12872317 AUTHORS Halperin JJ TITLE Lyme disease and the peripheral nervous system. JOURNAL Muscle Nerve 28:133-43 (2003) DOI:10.1002/mus.10337 PMID:21958583 AUTHORS Zajkowska J, Czupryna P, Pancewicz SA, Kondrusik M, Moniuszko A TITLE Acrodermatitis chronica atrophicans. JOURNAL Lancet Infect Dis 11:800 (2011) DOI:10.1016/S1473-3099(10)70121-3 PMID:15547252 AUTHORS Glockner G, Lehmann R, Romualdi A, Pradella S, Schulte-Spechtel U, Schilhabel M, Wilske B, Suhnel J, Platzer M. TITLE Comparative analysis of the Borrelia garinii genome. JOURNAL Nucleic Acids Res 32:6038-46 (2004) DOI:10.1093/nar/gkh953 |