| H00368 | |
| H number | H00368 |
| Name | Cytomegalovirus infection; CMV infection |
| Description | Cytomegalovirus (CMV) is a double-stranded DNA virus of the Herpesviridae family acquired by late childhood in the majority of individuals. Primary infection is nonspecific but after that the virus becomes latent in multiple organs and can later be reactivated. CMV is an important and common cause of mortality and morbidity in immunocompromised patients such as those with HIV/AIDS or transplant recipients on immunosuppressive therapy. |
| Category | Viral infectious disease DIS_PATHWAY hsa05163 Human cytomegalovirus infection |
| Network | nt06167 Human cytomegalovirus (HCMV) nt06516(H00368) TNF signaling nt06518(H00368) JAK-STAT signaling nt06520(H00368) CGAS-STING signaling nt06522(H00368) mTOR signaling nt06524(H00368) Apoptosis nt06526(H00368) MAPK signaling nt06530(H00368) PI3K signaling |
| Gene | - |
| Pathogen | Human herpesvirus 5 (Human cytomegalovirus) [GN:T40080] |
| Env factor | - |
| Carcinogen | - |
| Drug | Ganciclovir [DR:D00333] Ganciclovir sodium [DR:D04301] Cidofovir [DR:D00273] Valganciclovir hydrochloride [DR:D03256] Foscarnet sodium [DR:D00579] Maribavir [DR:D04859] Letermovir [DR:D10801] |
| Comment | - |
| Other DBs | ICD-11: 1D82 ICD-10: B20.2 B25 B27.1 P35.1 MeSH: D003586 |
| Reference | PMID:21970493 AUTHORS Chisholm C, Lopez L TITLE Cutaneous infections caused by Herpesviridae: a review. JOURNAL Arch Pathol Lab Med 135:1357-62 (2011) DOI:10.5858/arpa.2010-0156-RS PMID:21748845 AUTHORS Fishman JA TITLE Infections in immunocompromised hosts and organ transplant recipients: essentials. JOURNAL Liver Transpl 17 Suppl 3:S34-7 (2011) DOI:10.1002/lt.22378 PMID:21056604 AUTHORS Jackson SE, Mason GM, Wills MR TITLE Human cytomegalovirus immunity and immune evasion. JOURNAL Virus Res 157:151-60 (2011) DOI:10.1016/j.virusres.2010.10.031 PMID:21841300 AUTHORS Jain M, Duggal S, Chugh TD TITLE Cytomegalovirus infection in non-immunosuppressed critically ill patients. JOURNAL J Infect Dev Ctries 5:571-9 (2011) DOI:10.3855/jidc.1487 PMID:21827433 AUTHORS Ross SA, Novak Z, Pati S, Boppana SB TITLE Overview of the diagnosis of cytomegalovirus infection. JOURNAL Infect Disord Drug Targets 11:466-74 (2011) DOI:10.2174/187152611797636703 |