| H01167 | |
| H number | H01167 |
| Name | Granulibacter infection |
| Description | Granulibacter is a gram-negative acetic acid bacterium that is recently reported to be a human opportunistic pathogen. Granulibacter has been isolated from patients with chronic granulomatous disease, in which phagocytes are not able to produce bactericidal superoxide anions. Bacteremia has also been observed in a non-immunocompromised patient with a history of intravenous drug abuse. |
| Category | Bacterial infectious disease |
| Network | - |
| Gene | CYBB (Chronic granulomatous disease) [HSA:1536] [KO:K21421] CYBA (Chronic granulomatous disease) [HSA:1535] [KO:K08009] NCF1 (Chronic granulomatous disease) [HSA:653361] [KO:K08011] |
| Pathogen | Granulibacter bethesdensis [GN:gbe] |
| Env factor | - |
| Carcinogen | - |
| Drug | - |
| Comment | Chronic granulomatous disease is described in H00098. |
| Other DBs | - |
| Reference | PMID:16617373 AUTHORS Greenberg DE, Ding L, Zelazny AM, Stock F, Wong A, Anderson VL, Miller G, Kleiner DE, Tenorio AR, Brinster L, Dorward DW, Murray PR, Holland SM TITLE A novel bacterium associated with lymphadenitis in a patient with chronic granulomatous disease. JOURNAL PLoS Pathog 2:e28 (2006) DOI:10.1371/journal.ppat.0020028 PMID:17082400 AUTHORS Greenberg DE, Porcella SF, Stock F, Wong A, Conville PS, Murray PR, Holland SM, Zelazny AM TITLE Granulibacter bethesdensis gen. nov., sp. nov., a distinctive pathogenic acetic acid bacterium in the family Acetobacteraceae. JOURNAL Int J Syst Evol Microbiol 56:2609-16 (2006) DOI:10.1099/ijs.0.64412-0 PMID:17827295 AUTHORS Greenberg DE, Porcella SF, Zelazny AM, Virtaneva K, Sturdevant DE, Kupko JJ 3rd, Barbian KD, Babar A, Dorward DW, Holland SM. TITLE Genome sequence analysis of the emerging human pathogenic acetic acid bacterium Granulibacter bethesdensis. JOURNAL J Bacteriol 189:8727-36 (2007) DOI:10.1128/JB.00793-07 |