| H00297 | |
| H番号 | H00297 |
| 名称 | ペスト |
| 概要 | Plague is a deadly infectious disease caused by Yersinia pestis. The pathogen has rodent reservoirs and is transmitted to humans usually by fleas as vectors. There are three major manifestations: bubonic, septicemic, and pneumonic plagues. Severe epidemics in the past include the Plague of Justinian in the sixth century, the Black Death in the fourteenth century, and the Third Pandemic that began in Central Asia in the nineteenth century. The genome sequences have been determined for the strains responsible for these epidemics. |
| カテゴリ | 細菌感染症 |
| ネットワーク | nt06120(H00297) Calcium signaling (viruses and bacteria) nt06135(H00297) Cytoskeletal regulation (viruses and bacteria) nt06139(H00297) NLR signaling (viruses and bacteria) nt06517(H00297) TLR signaling nt06521(H00297) NLR signaling nt06528(H00297) Calcium signaling |
| 病因遺伝子 | - |
| 病原体 | Yersinia pestis CO92 (biovar Orientalis) [GN:ype] (Third Pandemic) Yersinia pestis KIM (biovar Mediaevalis) [GN:ypk] (Black Death) Yersinia pestis Antiqua,Nepal516 (biovar Antiqua) [GN:ypa ypn] (Plague of Justinian) Yersinia pestis Pestoides F [GN:ypp] Yersinia pestis Angola [GN:ypg] Yersinia pestis D106004 [GN:ypd] Yersinia pestis D182038 [GN:ypx] |
| 環境要因 | - |
| 発癌物質 | - |
| 治療薬 | レボフロキサシン水和物 [DR:D00588] ドキシサイクリン塩酸塩水和物 [DR:D02129] ストレプトマイシン硫酸塩 [DR:D01350] |
| コメント | Vector: Xenopsylla cheopis (rat flea) murine toxin [KO:K11009] |
| リンク | ICD-11: 1B93 ICD-10: A20 MeSH: D010930 MedlinePlus: 000596 |
| 文献 | - |