| H00304 | |
| H番号 | H00304 |
| 名称 | インフルエンザ菌感染症; ヘモフィルスインフルエンザ感染症; 侵襲性インフルエンザ菌感染症 |
| 概要 | Haemophilus influenzae type b (Hib) infections are a major cause of severe infections in children between 2 months and 5 years of age worldwide. It affects approximately 25000 patients each year. Severity of the symptoms of Hib infection depends on the patient's age, and infants between 4 months and 1 year of age are at highest risk for meningitis. Invasive disease due to Hib may produce various clinical syndromes including meningitis, arthritis, pneumonia, cellulitis, osteomyelitis, and epiglottitis. Mucosal infections, such as bronchitis, sinusitis and conjunctivitis, and otitis media, can also be caused by Hib, but they are considered to be noninvasive disease. |
| カテゴリ | 細菌感染症 |
| ネットワーク | - |
| 病因遺伝子 | - |
| 病原体 | Haemophilus influenzae [GN:hin hit hip hiq hiu hik hih] |
| 環境要因 | - |
| 発癌物質 | - |
| 治療薬 | 乾燥ヘモフィルスb型ワクチン [DR:D09189] 沈降精製百日せきジフテリア破傷風不活化ポリオヘモフィルスb型混合ワクチン [DR:D12585] |
| コメント | American Indians and Alaskan Eskimos are at increased risk specifically for meningitis caused by Hib. |
| リンク | ICD-11: 1D01.00 CA40.02 CA42.4 ICD-10: A41.3 A49.2 G00.0 J14 J20.1 MeSH: D006192 |
| 文献 | PMID:2194406 著者 Janai H, Stutman HR, Marks MI タイトル Invasive Haemophilus influenzae type B infections: a continuing challenge. 雑誌 Am J Infect Control 18:160-6 (1990) DOI:10.1016/0196-6553(90)90181-Q PMID:22244051 著者 Ladhani SN タイトル Two decades of experience with the Haemophilus influenzae serotype b conjugate vaccine in the United Kingdom. 雑誌 Clin Ther 34:385-99 (2012) DOI:10.1016/j.clinthera.2011.11.027 PMID:20980793 著者 Fitzwater SP, Watt JP, Levine OS, Santosham M タイトル Haemophilus influenzae type b conjugate vaccines: considerations for vaccination schedules and implications for developing countries. 雑誌 Hum Vaccin 6:810-8 (2010) DOI:10.4161/hv.6.10.13017 PMID:3325012 著者 Gilbert GL タイトル Epidemiology and prevention of invasive Haemophilus influenzae type b infection. 雑誌 Aust Paediatr J 23:323-7 (1987) DOI:10.1111/j.1440-1754.1987.tb00283.x |