| H00363 | |
| H number | H00363 |
| Name | Candidiasis |
| Description | Candidiasis is a fungal infection with Candida species, predominantly with Candida albicans. Invasive candidiasis is a major cause of morbidity and mortality in the intensive care unit (ICU) setting, causing bloodstream infections. Recently, various non-C. albicans species have emerged as infecting agents. In patients with impaired IL-17 immunity, recurrent or persistent infections are observed (chronic mucocutaneous candidiasis disease). |
| Category | Fungal infectious disease |
| Network | - |
| Gene | - |
| Pathogen | Candida albicans [GN:cal] Candida dubliniensis [GN:cdu] Candida tropicalis [GN:ctp] Candida glabrata [GN:cgr] Meyerozyma guilliermondii [GN:pgu] Clavispora lusitaniae [GN:clu clus] Candida auris [GN:caur] |
| Env factor | - |
| Carcinogen | - |
| Drug | Amphotericin B [DR:D00203] Miconazole [DR:D00416] Miconazole nitrate [DR:D00882] Clotrimazole [DR:D00282] Nystatin [DR:D00202] Fluconazole [DR:D00322] Flucytosine [DR:D00323] Butoconazole nitrate [DR:D00880] Terconazole [DR:D00888] Voriconazole [DR:D00578] Posaconazole [DR:D02555] Oteseconazole [DR:D11785] Caspofungin acetate [DR:D02501] Micafungin sodium [DR:D02465] Anidulafungin [DR:D03211] Ibrexafungerp citrate [DR:D11545] Rezafungin acetate [DR:D11198] |
| Comment | - |
| Other DBs | ICD-11: 1F23 ICD-10: B37 MeSH: D002177 |
| Reference | PMID:21486733 AUTHORS Rodloff C, Koch D, Schaumann R TITLE Epidemiology and antifungal resistance in invasive candidiasis. JOURNAL Eur J Med Res 16:187-95 (2011) DOI:10.1186/2047-783X-16-4-187 PMID:18279532 AUTHORS Mean M, Marchetti O, Calandra T TITLE Bench-to-bedside review: Candida infections in the intensive care unit. JOURNAL Crit Care 12:204 (2008) DOI:10.1186/cc6212 PMID:21350122 AUTHORS Puel A, Cypowyj S, Bustamante J, Wright JF, Liu L, Lim HK, Migaud M, Israel L, Chrabieh M, Audry M, Gumbleton M, Toulon A, Bodemer C, El-Baghdadi J, Whitters M, Paradis T, Brooks J, Collins M, Wolfman NM, Al-Muhsen S, Galicchio M, Abel L, Picard C, Casanova JL TITLE Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. JOURNAL Science 332:65-8 (2011) DOI:10.1126/science.1200439 PMID:21727188 AUTHORS Liu L, Okada S, Kong XF, Kreins AY, Cypowyj S, Abhyankar A, Toubiana J, Itan Y, Audry M, Nitschke P, Masson C, Toth B, Flatot J, Migaud M, Chrabieh M, Kochetkov T, Bolze A, Borghesi A, Toulon A, Hiller J, Eyerich S, Eyerich K, Gulacsy V, Chernyshova L, Chernyshov V, Bondarenko A, Maria Cortes Grimaldo R, Blancas-Galicia L, Madrigal Beas IM, Roesler J, Magdorf K, Engelhard D, Thumerelle C, Burgel PR, Hoernes M, Drexel B, Seger R, Kusuma T, Jansson AF, Sawalle-Belohradsky J, Belohradsky B, Jouanguy E, Bustamante J, Bue M, Karin N, Wildbaum G, Bodemer C, Lortholary O, Fischer A, Blanche S, Al-Muhsen S, Reichenbach J, Kobayashi M, Rosales FE, Lozano CT, Kilic SS, Oleastro M, Etzioni A, Traidl-Hoffmann C, Renner ED, Abel L, Picard C, Marodi L, Boisson-Dupuis S, Puel A, Casanova JL TITLE Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis. JOURNAL J Exp Med 208:1635-48 (2011) DOI:10.1084/jem.20110958 |