H number H00768
Name Nonsyndromic autosomal recessive mental retardation (NS-ARMR)
Description Mental retardation (MR) is a neurodevelopmental disorder characterized by low intelligence quotient (IQ) and deficits in adaptive behaviors. Although X-linked MR has been extensively studied, and over 80 causal genes have been cloned, little is known about the genetic basis of nonsyndromic autosomal-recessive mental retardation (NS-ARMR). To date, several genes have been identified for NS-ARMR. These genes have a variety of functions and participate in multiple biochemical pathways. In addition, there are several known disease loci for NS-ARMR for which genes have not yet been identified.
Category Congenital disorder; Mental retardation