H01553
H number H01553
Name Zika fever;
Zika virus disease
Description Zika fever is one of the mosquito-borne viral fevers caused by Zika virus (ZIKV), genus Flavivirus, family Flaviviridae. ZIKV is transmissible from human to human through bites of Aedes species. ZIKV was initially distinguished in rhesus monkeys in the Zika forest of Uganda throughout the period of a yellow fever study. No outbreak had been reported until 2007, when ZIKV spread further to the Pacific Island of Yap. In 2013, the second and largest outbreak occurred in French Polynesia. In 2015, ZIKV infection has been confirmed in 18 states of Brazil, and the geographical distribution of ZIKV has steadily broadened given the wide distribution of the mosquito vector. Clinical manifestations of infection include fever, headache, retro-orbital pain, arthralgia, malaise, myalgia, anorexia, rash, oedema, lymphadenopathy and diarrhoea. In most cases, the infection appeared mild and self-limiting, with a mean symptom duration of 3-6 days. Shock complications and haemorrhagic signs have not been reported. However, Guillain-Barre syndrome, a neurologic complication, was reported. Clinical and epidemiological study showed that there is a link between microcephaly and of Zika virus. It has been reported that ZIKV-infected children, who were born to ZIKV-infected mothers during pregnancy, were found to have neonatal head circumferences below the 10th percentile.
Category Infectious disease