H01410 | |
H number | H01410 |
Name | Anaerobic infection |
Description | Anaerobic infections are common and some are serious with a high mortality rate. The clinically important anaerobes are several genera of Gram-negative rods (Bacteroides, Prevotella, Porphyromonas, Fusobacterium and Bilophila). Among the Gram-positive anaerobes, there are cocci (primarily Peptostreptococcus) and sporeforming (Clostridium) and non-sporeforming bacilli (especially Actinomyces and Propionibacterium). In terms of frequency, there are four major sites of anaerobic infection - pleuropulmonary, intra-abdominal, female genital tract, and skin and soft tissue infections (with or without involvement of underlying bone). Infectious diseases caused by these anaerobes include following symptoms, bacteremia, brain abscess, neck space infections and infections following head and neck surgery, chronic sinusitis and otitis media, dental and oral infections, pleuropulmonary infections, intra-abdominal infections, female genital tract infections, non-puerperal breast abscesses and diabetic foot ulcers. |
Category | Bacterial infectious disease |
Network | - |
Gene | - |
Pathogen | - |
Env factor | - |
Carcinogen | - |
Drug | Metronidazole [DR:D00409] |
Comment | Infectious disease caused by Bacteroides spp., Prevotella spp., Porphyromonas spp., Porphyromonas spp., Fusobacterium spp., Peptostreptococcus spp., Clostridium spp., Bilophila spp. and Actinomyces spp.. |
Other DBs | ICD-10: A49 B96 |
Reference | PMID:16887500 AUTHORS Finegold SM TITLE Anaerobic infections in humans: an overview. JOURNAL Anaerobe 1:3-9 (1995) DOI:10.1016/S1075-9964(95)80340-8 PMID:18263572 AUTHORS Goto T, Yamashita A, Hirakawa H, Matsutani M, Todo K, Ohshima K, Toh H, Miyamoto K, Kuhara S, Hattori M, Shimizu T, Akimoto S. TITLE Complete genome sequence of Finegoldia magna, an anaerobic opportunistic pathogen. JOURNAL DNA Res 15:39-47 (2008) DOI:10.1093/dnares/dsm030 |