| H00314 | |
| H number | H00314 |
| Name | Meningococcal infection |
| Description | Neisseria meningitidis is a gram-negative bacterial pathogen that specifically infects humans. It is a frequent asymptomatic colonizer of the human upper respiratory tract, and most adults are resistant to infection through acquired immunity. In susceptible individuals, it causes meningococcal meningitis and severe septicemia. |
| Category | Bacterial infectious disease |
| Network | - |
| Gene | - |
| Pathogen | Neisseria meningitidis serogroup A [GN:nma nmw nmx] Neisseria meningitidis serogroup B [GN:nme nmh nmd nmm nms nmq nmz] Neisseria meningitidis serogroup C [GN:nmc nmn nmt] |
| Env factor | - |
| Carcinogen | - |
| Drug | Penicillin G potassium [DR:D01053] Sulfadiazine [DR:D00587] |
| Comment | Antibiotic resistance in N. meningitidis ash been reported. |
| Other DBs | ICD-11: 1C1C ICD-10: A39 MeSH: D008589 |
| Reference | PMID:19287450 AUTHORS Virji M TITLE Pathogenic neisseriae: surface modulation, pathogenesis and infection control. JOURNAL Nat Rev Microbiol 7:274-86 (2009) DOI:10.1038/nrmicro2097 PMID:12150701 AUTHORS Foster C, Nadel S TITLE New therapies and vaccines for bacterial meningitis. JOURNAL Expert Opin Investig Drugs 11:1051-60 (2002) DOI:10.1517/13543784.11.8.1051 PMID:22085175 AUTHORS Safadi MA, McIntosh ED TITLE Epidemiology and prevention of meningococcal disease: a critical appraisal of vaccine policies. JOURNAL Expert Rev Vaccines 10:1717-30 (2011) DOI:10.1586/erv.11.159 PMID:21832882 AUTHORS Yogev R, Tan T TITLE Meningococcal disease: the advances and challenges of meningococcal disease prevention. JOURNAL Hum Vaccin 7:828-37 (2011) DOI:10.4161/hv.7.8.16270 |