| H00373 | |
| H number | H00373 |
| Name | Mpox (Monkeypox) |
| Description | Human monkeypox is a rare viral zoonotic disease caused by Monkeypox virus of the genus Orthopoxvirus. It occurs mostly in the rain forests of central and western Africa. Human monkeypox has a clinical presentation similar to that of smallpox, including characteristic rash. Lymphadenopathy is not a common feature of smallpox and is therefore a key distinguishing feature of monkeypox. By contrast with smallpox, human monkeypox has low transmissibility between human beings. |
| Category | Viral infectious disease |
| Network | - |
| Gene | - |
| Pathogen | Monkeypox virus [GN:T40083] |
| Env factor | - |
| Carcinogen | - |
| Drug | - |
| Comment | Many animals are infected with monkeypox virus under natural conditions, including squirrels, non-human primates, and rats. However, the primary reservoir for human infection remains unknown. |
| Other DBs | ICD-11: 1E71 ICD-10: B04 MeSH: D045908 |
| Reference | PMID:6304185 AUTHORS Jezek Z, Gromyko AI, Szczeniowski MV TITLE Human monkeypox. JOURNAL J Hyg Epidemiol Microbiol Immunol 27:13-28 (1983) PMID:16288402 AUTHORS Nalca A, Rimoin AW, Bavari S, Whitehouse CA TITLE Reemergence of monkeypox: prevalence, diagnostics, and countermeasures. JOURNAL Clin Infect Dis 41:1765-71 (2005) DOI:10.1086/498155 PMID:17661673 AUTHORS Parker S, Nuara A, Buller RM, Schultz DA TITLE Human monkeypox: an emerging zoonotic disease. JOURNAL Future Microbiol 2:17-34 (2007) DOI:10.2217/17460913.2.1.17 |