| DG00023 | |
| DG number | DG00023 |
| Classification | Chemical DGroup |
| Name | Esomeprazole |
| Stem | - |
| Structural formula | - |
| Member | D07917 Esomeprazole (INN) D01984 Esomeprazole magnesium (USAN); Esomeprazole magnesium hydrate (JAN) D04056 Esomeprazole sodium (USAN) D09339 Esomeprazole potassium (USAN) D10120 Esomeprazole strontium (USAN) |
| Upper group | Gastrointestinal agent DG01646 Proton pump inhibitor (PPI) DG01975 Agents for peptic ulcer DG01646 Proton pump inhibitor (PPI) Cyp substrate DG01639 CYP2C19 substrate DG01633 CYP3A substrate Cyp inhibitor DG01933 CYP2C19 inhibitor Cyp inducer DG01637 CYP1A2 inducer |
| Remark | ATC code: A02BC05 |
| Comment | Antiulcer agent, proton pump inhibitor |
| Target | ATP4A [HSA:495] [KO:K01542] ATP4B [HSA:496] [KO:K01543] |
| Metabolism | Enzyme: CYP2C19 [HSA:1557], CYP3A4 [HSA:1576] |
| Interaction | Genomic biomarker: CYP2C19 [HSA:1557] CYP induction: CYP1A2 [HSA:1544] CYP inhibition: CYP2C19 [HSA:1557] |