Kegg medicus dgroup en
| DG01644 | |
| DG number | DG01644 |
| Classification | DGroup |
| Name | CYP2D6 substrate TYPE Metabolism |
| Stem | - |
| Structural formula |  |
| Member | D01131 Lafutidine (JP18/INN) DG03104 Vonoprazan D11784 Vonoprazan (USAN/INN) D10466 Vonoprazan fumarate (JAN/USAN) D10775 Vonoprazan, amoxicillin and clarithromycin D10774 Vonoprazan, amoxicillin and metronidazole DG00055 Metoclopramide D00726 Metoclopramide (JP18/INN) D02213 Metoclopramide hydrochloride (JAN) D05008 Metoclopramide hydrochloride (USP) DG00060 Ondansetron D00456 Ondansetron (JAN/USP/INN) D00678 Ondansetron hydrochloride hydrate (JAN/USP) DG00063 Dolasetron D07867 Dolasetron (INN) D00725 Dolasetron mesylate (USP) DG00064 Palonosetron D07175 Palonosetron (INN) D05343 Palonosetron hydrochloride (JAN/USP) D10572 Fosnetupitant and palonosetron hydrochloride DG00103 Fenfluramine D07945 Fenfluramine (INN) D04148 Fenfluramine hydrochloride (JAN/USAN) DG00105 Dexfenfluramine D07805 Dexfenfluramine (INN) D03713 Dexfenfluramine hydrochloride (USAN) DG00112 Phenformin D08351 Phenformin (BAN) D08352 Phenformin hydrochloride DG00148 Eliglustat D09893 Eliglustat (USAN/INN) D09894 Eliglustat tartrate (JAN/USAN) D01896 Cilostazol (JP18/USP/INN) DG00195 Sparteine D01041 Sparteine (INN) D02239 Sparteine sulfate (JAN/USAN) D00199 Ajmaline (JP18) DG00197 Mexiletine D08215 Mexiletine (INN) D00639 Mexiletine hydrochloride (JP18/USP) DG00199 Aprindine D02969 Aprindine (USAN/INN) D01326 Aprindine hydrochloride (JP18/USAN) DG00200 Propafenone D08435 Propafenone (INN) D00640 Propafenone hydrochloride (JP18/USP) DG00201 Flecainide D07962 Flecainide (INN) D00638 Flecainide acetate (JP18/USP) DG00203 Encainide D07894 Encainide (INN) D03991 Encainide hydrochloride (USAN) DG00209 Cibenzoline D03492 Cifenline (USAN); Cibenzoline (INN) D01455 Cifenline succinate (USAN); Cibenzoline succinate (JP18) DG00257 Urapidil D01333 Urapidil (JP18/INN) D08662 Urapidil hydrochloride D03664 Debrisoquin sulfate (USAN) DG00303 Alprenolol D07156 Alprenolol (INN) D01182 Alprenolol hydrochloride (JP18/USAN) D00513 Pindolol (JP18/USP/INN) DG00305 Propranolol D08443 Propranolol (INN) D00483 Propranolol hydrochloride (JP18/USP) DG00306 Timolol D08600 Timolol (INN) D00378 Timolol (USAN) D00603 Timolol maleate (JP18/USP) DG00308 Carteolol D07624 Carteolol (INN) D00599 Carteolol hydrochloride (JP18/USP) DG00310 Bopindolol D07537 Bopindolol (INN) D01794 Bopindolol malonate (JAN) DG00313 Metoprolol D02358 Metoprolol (USAN/INN) D00601 Metoprolol tartrate (JP18/USP) D00635 Metoprolol succinate (USP) D05011 Metoprolol fumarate (USP) D00235 Atenolol (JP18/USP/INN) DG00319 Nebivolol D05127 Nebivolol (USAN/INN) D06622 Nebivolol hydrochloride (USAN) DG00321 Carvedilol D00255 Carvedilol (JP18/USP/INN) D03415 Carvedilol phosphate (USAN); Carvedilol phosphate hydrate (JAN) D10273 Metoprolol and hydrochlorothiazide DG00333 Bepridil D07520 Bepridil (INN) D00631 Bepridil hydrochloride (USAN); Bepridil hydrochloride hydrate (JAN) DG00334 Perhexiline D08340 Perhexiline (INN) D05442 Perhexiline maleate (USAN) DG00385 Promethazine D00494 Promethazine (JAN/INN) D00480 Promethazine hydrochloride (JP18/USP) D01242 Promethazine teoclate (JAN/INN) D03290 Promethazine methylenedisalicylate (JAN) D08432 Promethazine maleate D08768 Promethazine hibenzate DG00937 Doxepin D07875 Doxepin (INN) D00814 Doxepin hydrochloride (USP) DG00480 Tolterodine D00646 Tolterodine (USAN/INN) D01148 Tolterodine tartrate (JAN/USP) DG00482 Darifenacin D03654 Darifenacin (USAN/INN) D01699 Darifenacin hydrobromide (JAN/USAN) DG00483 Fesoterodine D07226 Fesoterodine (INN) D08923 Fesoterodine fumarate (JAN/USAN) D11389 Dutasteride and tamsulosin D12137 Elagolix, estradiol and norethisterone DG02839 Osilodrostat D11061 Osilodrostat (USAN/INN) D11062 Osilodrostat phosphate (JAN/USAN) D01078 Telithromycin (JAN/USAN/INN) D09785 Delamanid (JAN/USAN) D00427 Ritonavir (JAN/USP/INN) D00435 Nevirapine (JAN/USP/INN) D10756 Elvitegravir, cobicistat, emtricitabine and tenofovir disoproxil DG00734 Tamoxifen D08559 Tamoxifen (INN) D00966 Tamoxifen citrate (JP18/USP) DG02829 Upadacitinib D10994 Upadacitinib (USAN/INN) D10995 Upadacitinib tartrate (USAN) D11048 Upadacitinib hydrate (JAN) D11817 Deucravacitinib (JAN/USAN) D01583 Pirfenidone (JAN/USAN/INN) DG00813 Oxycodone D05312 Oxycodone (USAN/INN) D00847 Oxycodone hydrochloride (USP) D02175 Compound oxycodone (JP18) D03783 Oxycodone terephthalate (USP) D05462 Oxycodone hydrochloride hydrate (JP18) DG00814 Dihydrocodeine D07831 Dihydrocodeine (INN) D01481 Dihydrocodeine phosphate (JP18) D03825 Dihydrocodeine bitartrate (USP) D07832 Dihydrocodeine thiocyanate D08695 dl-Methylephedrine hydrochloride, dihydrocodeine phosphate, diprophylline, diphenhydramine salicylate, acetaminophen and bromovalerylurea D09999 Tramadol hydrochloride and acetaminophen DG00824 Tramadol D08623 Tramadol (INN) D01355 Tramadol hydrochloride (JP18/USP) DG00837 Naratriptan D08255 Naratriptan (INN) D00674 Naratriptan hydrochloride (JAN/USP) DG00839 Almotriptan D02824 Almotriptan (USAN) D02825 Almotriptan malate (USP) D04300 Ganaxolone (USAN/INN) DG00864 Selegiline D03731 Selegiline (USAN/INN) D00785 Selegiline hydrochloride (JAN/USP) DG00867 Chlorpromazine D00270 Chlorpromazine (USP/INN) D00789 Chlorpromazine hydrochloride (JP18/USP) D03274 Chlorpromazine hibenzate (JAN) D04034 Chlorpromazine phenolphthalinate (JAN) D09819 Chlorpromazine tannate (JAN) DG00874 Fluphenazine D07977 Fluphenazine (INN) D00791 Fluphenazine hydrochloride (JAN/USP) D00792 Fluphenazine enanthate (JP18/USP) D00793 Fluphenazine decanoate (JAN/USP) D02163 Fluphenazine maleate (JAN) DG00875 Perphenazine D00503 Perphenazine (JP18/USP/INN) D02037 Perphenazine maleate (JP18) D04038 Perphenazine fendizoate (JAN) D04965 Perphenazine hydrochloride D08341 Perphenazine decanoate D08342 Perphenazine enantate DG00885 Haloperidol D00136 Haloperidol (JP18/USP/INN) D01898 Haloperidol decanoate (JAN/USP) D08035 Haloperidol lactate DG00896 Zuclopenthixol D03556 Zuclopenthixol (INN) D08691 Zuclopenthixol acetate D08692 Zuclopenthixol decanoate D08693 Zuclopenthixol dihydrochloride D00560 Pimozide (JP18/USP/INN) DG00897 Loxapine D02340 Loxapine (USAN/INN) D00794 Loxapine succinate (USP) D08148 Loxapine hydrochloride DG00898 Olanzapine D00454 Olanzapine (JAN/USP/INN) D06623 Olanzapine pamoate (USAN) D00426 Risperidone (JP18/USP/INN) DG00906 Aripiprazole D01164 Aripiprazole (JAN/USP/INN) D10355 Aripiprazole cavoxil (USAN) D10364 Aripiprazole lauroxil (USAN) D10516 Aripiprazole hydrate (JAN) D02666 Iloperidone (USAN/INN) DG01305 Cariprazine D09997 Cariprazine (USAN/INN) D09876 Cariprazine hydrochloride (JAN/USAN) D10309 Brexpiprazole (JAN/USAN/INN) D08969 Pimavanserin tartrate (USAN) D02615 Chlorpromazine hydrochloride, promethazine hydrochloride and phenobarbital DG00926 Dexmedetomidine D00514 Dexmedetomidine (USAN/INN) D01205 Dexmedetomidine hydrochloride (JAN/USP) DG00928 Imipramine D08070 Imipramine (INN) D00815 Imipramine hydrochloride (JP18/USP) D08071 Imipramine pamoate (USP) DG00929 Clomipramine D07727 Clomipramine (INN) D00811 Clomipramine hydrochloride (JP18/USP) DG00934 Amitriptyline D07448 Amitriptyline (INN) D00809 Amitriptyline hydrochloride (JP18/USP) DG00935 Nortriptyline D08288 Nortriptyline (INN) D00816 Nortriptyline hydrochloride (JP18/USP/INN) DG00940 Dosulepin D07872 Dosulepin (INN) D01546 Dothiepin hydrochloride (USAN); Dosulepin hydrochloride (JAN) D00228 Amoxapine (JP18/USP/INN) DG00941 Maprotiline D02566 Maprotiline (USAN) D00818 Maprotiline hydrochloride (JP18/USP) DG00942 Fluoxetine D00326 Fluoxetine (USAN/INN) D00823 Fluoxetine hydrochloride (JAN/USP) DG00943 Citalopram D07704 Citalopram (USP/INN) D00822 Citalopram hydrobromide (USP) D07705 Citalopram hydrochloride DG00944 Paroxetine D02362 Paroxetine (USP/INN) D02260 Paroxetine hydrochloride hemihydrate (USP); Paroxetine hydrochloride hydrate (JP18) D05374 Paroxetine hydrochloride (USP) D05375 Paroxetine mesylate (USAN) DG00946 Fluvoxamine D07984 Fluvoxamine (INN) D00824 Fluvoxamine maleate (JP18/USP) DG00947 Escitalopram D07913 Escitalopram (INN) D02567 Escitalopram oxalate (JAN/USP) DG00951 Mianserin D08216 Mianserin (INN) D01358 Mianserin hydrochloride (JAN/USAN) DG00952 Trazodone D08626 Trazodone (INN) D00820 Trazodone hydrochloride (JAN/USP) DG00954 Minaprine D05039 Minaprine (USAN/INN) D05040 Minaprine hydrochloride (USAN) DG00956 Viloxazine D08673 Viloxazine (INN) D02572 Viloxazine hydrochloride (USAN) DG02838 Mirtazapine D00563 Mirtazapine (JAN/USP/INN) D11056 Mirtazapine hydrate (JAN) DG00959 Venlafaxine D08670 Venlafaxine (INN) D00821 Venlafaxine hydrochloride (JAN/USP) D12403 Venlafaxine besylate monohydrate DG00962 Duloxetine D07880 Duloxetine (INN) D01179 Duloxetine hydrochloride (JAN/USP) DG00964 Vilazodone D09698 Vilazodone (USAN/INN) D09699 Vilazodone hydrochloride (USAN) DG00965 Vortioxetine D10184 Vortioxetine (USAN) D10185 Vortioxetine hydrobromide (JAN/USAN) D12544 Vortioxetine hemihydrobromide (USAN) DG00966 Amfetamine D07445 Amfetamine (INN) D02074 Amphetamine sulfate (USP) DG00967 Dexamfetamine D03740 Dextroamphetamine (USAN); Dexamfetamine (INN) D02078 Dextroamphetamine sulfate (USP) DG00968 Metamfetamine D08187 Metamfetamine (INN) D02242 Methamphetamine hydrochloride (JP18/USP) DG00970 Atomoxetine D07473 Atomoxetine (USP/INN) D02574 Atomoxetine hydrochloride (JAN/USP) DG00983 Donepezil D07869 Donepezil (JAN/INN) D00670 Donepezil hydrochloride (JP18/USP) DG00985 Galantamine D04292 Galantamine (USAN/INN) D02173 Galantamine hydrobromide (JAN/USP) DG00993 Cevimeline D07667 Cevimeline (INN) D00661 Cevimeline hydrochloride (USAN); Cevimeline hydrochloride hydrate (JAN) DG00999 Methadone D08195 Methadone (BAN) D02102 Methadone hydrochloride (JAN/USP) DG01005 Cinnarizine D01295 Cinnarizine (JAN/USAN/INN) D07734 Cinnarizine dihydrochloride DG01006 Flunarizine D07971 Flunarizine (INN) D01303 Flunarizine hydrochloride (JAN/USAN) D08575 Tetrabenazine (JAN/INN) DG03021 Pitolisant D10749 Pitolisant (USAN/INN) D11490 Pitolisant hydrochloride (USAN) DG02115 Valbenazine D10675 Valbenazine (USAN/INN) D10999 Valbenazine tosylate (USAN); Valbenazine tosilate (JAN) D12493 Dextromethorphan hydrobromide and bupropion hydrochloride D10533 Umeclidinium bromide and vilanterol DG01075 Hydrocodone D08045 Hydrocodone (INN) D03725 Hydrocodone bitartrate (USP) D04461 Hydrocodone polistirex (USAN) D08046 Hydrocodone hydrochloride DG01076 Codeine C06174 Codeine D00195 Codeine (USP) D02101 Codeine phosphate (USP); Codeine phosphate hydrate (JP18) D03579 Codeine polistirex (USAN) D03580 Codeine sulfate (USP) D07740 Codeine hydrochloride DG01078 Dextromethorphan D03742 Dextromethorphan (USP) D00848 Dextromethorphan hydrobromide (USP); Dextromethorphan hydrobromide hydrate (JP18) D03744 Dextromethorphan polistirex (USAN) D12312 Codeine phosphate and chlorpheniramine maleate D04340 Dextromethorphan hydrobromide and potassium cresolsulfonate DG01098 Dexchlorpheniramine D07803 Dexchlorpheniramine (INN) D00668 Dexchlorpheniramine maleate (USP); d-Chlorpheniramine maleate (JP18) D04313 Dihydrocodeine phosphate, dl-methylephedrine hydrochloride and Chlorpheniramine maleate D12313 Chlorpheniramine polistirex and codeine polistirex D01324 Mequitazine (JP18/INN) D00364 Loratadine (JAN/USP/INN) D10512 Brinzolamide and timolol maleate D08493 Dorzolamide hydrochloride and timolol maleate (JP18) D09881 Cobicistat (JAN/USAN/INN) DG01239 Ramosetron D08466 Ramosetron (INN) D02016 Ramosetron hydrochloride (JAN) DG01253 Umeclidinium D10180 Umeclidinium (USAN) D10181 Umeclidinium bromide (JAN/USAN) DG01284 Trelagliptin D10178 Trelagliptin (USAN) D10179 Trelagliptin succinate (JAN/USAN) DG01333 Sarpogrelate D08508 Sarpogrelate (INN) D01624 Sarpogrelate hydrochloride (JP18) D01444 Bunitrolol hydrochloride (JAN) D04338 Dihydrocodeine phosphate, ephedrine hydrochloride and ammmonium chloride D08697 Platycodon fluidextract, glycyrrhiza extract, plantago herb extract, peony root extract and dihydrocodeine phosphate D11628 Benzhydrocodone and acetaminophen D11860 Butalbital, aspirin, caffeine and codeine DG01850 Benzhydrocodone D10612 Benzhydrocodone (USAN/INN) D10692 Benzhydrocodone hydrochloride (USAN) D11851 Butalbital, acetaminophen, caffeine and codeine phosphate |
| Upper group | Metabolizing enzyme substrate |
| Remark | - |
| Comment | - |