Kegg medicus dgroup
| DG01633 | |
| DG番号 | DG01633 |
| 分類 | DGroup |
| 名称 | CYP3A/CYP3A4 substrate TYPE Metabolism |
| ステム | - |
| 構造式 |  |
| メンバー | DG02913 CYP3A4 substrate DG00011 Dexamethasone D00292 Dexamethasone (JP18/USP/INN) D00975 Dexamethasone sodium phosphate (JAN/USP) D01510 Dexamethasone metasulfobenzoate sodium (JAN) D01615 Dexamethasone palmitate (JAN) D01632 Dexamethasone dipropionate (USAN); Dexamethasone propionate (JAN) D01948 Dexamethasone valerate (JAN) D02174 Dexamethasone acetate (JAN/USP) D02591 Dexamethasone acefurate (USAN/INN) D02592 Dexamethasone beloxil (USAN) D07073 Dexamethasone cipecilate (JAN/INN) D07796 Dexamethasone 21-acetate D07797 Dexamethasone isonicotinate D07798 Dexamethasone sodium hemisulfate D07799 Dexamethasone 21-tebutate D07800 Dexamethasone 21-valerate D07801 Dexamethasone phenylpropionate D07802 Dexamethasone phosphate D01131 Lafutidine (JP18/INN) DG00020 Omeprazole D00455 Omeprazole (JP18/USP/INN) D01207 Omeprazole sodium (USAN) D05261 Omeprazole sodium injection (JAN) D05259 Omeprazole magnesium (USP) DG00021 Pantoprazole D05353 Pantoprazole (USAN/INN) D02593 Pantoprazole sodium (USP); Pantoprazole sodium hydrate (JAN) D00355 Lansoprazole (JP18/USP/INN) DG00022 Rabeprazole D08463 Rabeprazole (INN) D00724 Rabeprazole sodium (JP18/USP) DG00023 Esomeprazole D07917 Esomeprazole (INN) D01984 Esomeprazole magnesium (USP); Esomeprazole magnesium hydrate (JAN) D04056 Esomeprazole sodium (USAN) D09339 Esomeprazole potassium (USAN) D10120 Esomeprazole strontium (USAN) D11114 Esomeprazole magnesium dihydrate D08903 Dexlansoprazole (INN/USAN) DG03104 Vonoprazan D11784 Vonoprazan (USAN/INN) D10466 Vonoprazan fumarate (JAN/USAN) D09742 Lansoprazole, amoxicillin hydrate and metronidazole D10246 Omeprazole, clarithromycin and amoxicillin D08774 Amoxicillin hydrate, clarithromycin and lansoprazole D10519 Rabeprazole, amoxicillin and clarithromycin D10520 Rabeprazole, amoxicillin and metronidazole D10775 Vonoprazan, amoxicillin and clarithromycin D10774 Vonoprazan, amoxicillin and metronidazole D01121 Rebamipide (JP18/INN) DG00046 Alosetron D07129 Alosetron (INN) D02829 Alosetron hydrochloride (USAN) DG00057 Domperidone D01745 Domperidone (JP18/USAN/INN) D07868 Domperidone maleate DG01285 Mosapride D01994 Mosapride citrate hydrate (JP18) D08236 Mosapride (INN) DG00060 Ondansetron D00456 Ondansetron (JAN/USP/INN) D00678 Ondansetron hydrochloride hydrate (JAN/USP) DG00061 Granisetron D04370 Granisetron (JAN/USAN/INN) D00677 Granisetron hydrochloride (JAN/USP) DG00064 Palonosetron D07175 Palonosetron (INN) D05343 Palonosetron hydrochloride (JAN/USP) D10572 Fosnetupitant and palonosetron hydrochloride DG00066 Aprepitant D02968 Aprepitant (JAN/USP/INN) D10895 Fosaprepitant (INN) D06597 Fosaprepitant dimeglumine (USAN); Fosaprepitant meglumine (JAN) DG01868 Rolapitant D10742 Rolapitant (USAN/INN) D08988 Rolapitant hydrochloride (USAN) DG01342 Naldemedine D10188 Naldemedine (USAN/INN) D10478 Naldemedine tosylate (JAN/USAN) DG03072 Tenapanor D11652 Tenapanor (USAN/INN) D11653 Tenapanor hydrochloride (JAN/USAN) D02554 Rifaximin (JAN/USAN/INN) DG00092 Loperamide D08144 Loperamide (INN) D00729 Loperamide hydrochloride (JAN/USP) D07113 Loperamide oxide (INN) D00246 Budesonide (JP18/USP/INN) D00689 Beclomethasone dipropionate (USP); Beclometasone dipropionate (JP18) D11572 Beclomethasone dipropionate monohydrate DG00103 Fenfluramine D07945 Fenfluramine (INN) D04148 Fenfluramine hydrochloride (JAN/USAN) D11710 Phentermine and topiramate D00336 Glyburide (USP); Glibenclamide (JP18/INN) D10263 Metformin hydrochloride and saxagliptin hydrochloride DG00119 Saxagliptin D08996 Saxagliptin (USAN/INN) D09753 Saxagliptin hydrate (JAN) D10262 Saxagliptin hydrochloride DG01283 Teneligliptin D08616 Teneligliptin (INN) D09756 Teneligliptin hydrobromide hydrate (JAN) D11968 Teneligliptin hydrobromide (JAN) D10669 Sotagliflozin (USAN/INN) D00594 Repaglinide (JAN/USP/INN) DG00148 Eliglustat D09893 Eliglustat (USAN/INN) D09894 Eliglustat tartrate (JAN/USAN) DG00155 Clopidogrel D07729 Clopidogrel (USP/INN) D00769 Clopidogrel bisulfate (USP); Clopidogrel sulfate (JP18); Clopidogrel sulfate tablets (JP18) D10823 Clopidogrel hydrochloride D10824 Clopidogrel besilate D01896 Cilostazol (JP18/USP/INN) DG01349 Vorapaxar D09765 Vorapaxar (USAN/INN) D09766 Vorapaxar sulfate (JAN/USAN) D09994 Selexipag (JAN/USAN/INN) D10513 Clopidogrel sulfate and aspirin D10527 Acetylsalicylic acid and lansoprazole DG00163 Argatroban C04931 Argatroban D00181 Argatroban (USP); Argatroban hydrate (JP18) D07086 Rivaroxaban (JAN/USAN/INN) D03213 Apixaban (JAN/USAN/INN) DG01976 Avatrombopag D10306 Avatrombopag (USAN/INN) D10307 Avatrombopag maleate (JAN/USAN) DG01419 Fostamatinib D09347 Fostamatinib (USAN) D09348 Fostamatinib disodium (USAN); Fostamatinib sodium hydrate (JAN) D11330 Voxelotor (USAN) DG00194 Disopyramide D00303 Disopyramide (JP18/USAN/INN) D00637 Disopyramide phosphate (JAN/USP) DG00196 Lidocaine D00358 Lidocaine (JP18/USP/INN) D02086 Lidocaine hydrochloride (JAN/USP) D08127 Lidocaine hydrochloride monohydrate DG00200 Propafenone D08435 Propafenone (INN) D00640 Propafenone hydrochloride (JP18/USP) DG00204 Amiodarone D02910 Amiodarone (USAN/INN) D00636 Amiodarone hydrochloride (JP18/USP) DG00209 Cibenzoline D03492 Cifenline (USAN); Cibenzoline (INN) D01455 Cifenline succinate (USAN); Cibenzoline succinate (JP18) DG00246 Ivabradine D07165 Ivabradine (USAN/INN) D08095 Ivabradine hydrochloride (JAN/USAN) D12265 Mavacamten (USAN/INN) DG00250 Guanfacine D08031 Guanfacine (INN) D00606 Guanfacine hydrochloride (JAN/USP) DG00266 Bosentan D07538 Bosentan (INN) D01227 Bosentan (USAN); Bosentan hydrate (JAN) D10135 Macitentan (JAN/USAN) D01115 Eplerenone (JP18/USAN/INN) D10633 Finerenone (JAN/USAN/INN) D01213 Tolvaptan (JAN/USAN/INN) DG00331 Diltiazem D07845 Diltiazem (INN) D00616 Diltiazem hydrochloride (JP18/USP) D03830 Diltiazem malate (USAN) DG00321 Carvedilol D00255 Carvedilol (JP18/USP/INN) D03415 Carvedilol phosphate (USAN); Carvedilol phosphate hydrate (JAN) DG00322 Amlodipine D07450 Amlodipine (USP/INN) D00615 Amlodipine besylate (USP); Amlodipine besilate (JP18) D02914 Amlodipine maleate (USAN) D11881 Amlodipine benzoate D00319 Felodipine (JP18/USP/INN) DG00323 Nicardipine D08270 Nicardipine (INN) D00617 Nicardipine hydrochloride (JP18/USAN) D00437 Nifedipine (JP18/USP/INN) D00438 Nimodipine (USP/INN) D00618 Nisoldipine (JAN/USAN/INN) D00629 Nitrendipine (JP18/USAN/INN) D01908 Nilvadipine (JP18/USAN/INN) DG00324 Manidipine D08155 Manidipine (INN) D01553 Manidipine hydrochloride (JP18) DG00325 Barnidipine D07494 Barnidipine (INN) D01104 Barnidipine hydrochloride (JAN) D01173 Cilnidipine (JP18/INN) DG00327 Benidipine D07509 Benidipine (INN) D02045 Benidipine hydrochloride (JP18) DG00329 Verapamil D02356 Verapamil (USAN/INN) D00619 Verapamil hydrochloride (JP18/USP) DG00333 Bepridil D07520 Bepridil (INN) D00631 Bepridil hydrochloride (USAN); Bepridil hydrochloride hydrate (JAN) D09745 Valsartan and amlodipine besilate D09743 Telmisartan and amlodipine besilate (JP18) D10243 Irbesartan and amlodipine besilate (JP18) D07569 Candesartan cilexetil and anmlodipine besylate (JP18) D10805 Telmisartan, amlodipine and hydrochlorothiazide DG00352 Aliskiren D03208 Aliskiren (USAN/INN) D06412 Aliskiren fumarate (JAN/USAN) D00434 Simvastatin (JP18/USP/INN) D00359 Lovastatin (USP/INN) DG00354 Fluvastatin D07983 Fluvastatin (INN) D00892 Fluvastatin sodium (JAN/USP) DG00355 Atorvastatin D07474 Atorvastatin (INN) D00887 Atorvastatin calcium anhydorous D02258 Atorvastatin calcium (USP); Atorvastatin calcium hydrate (JP18) D11095 Atorvastatin calcium propylene glycol solvate DG00356 Cerivastatin D07661 Cerivastatin (INN) D00889 Cerivastatin sodium (JAN/USAN) DG00362 Lomitapide D09637 Lomitapide (USAN/INN) D09638 Lomitapide mesylate (USAN); Lomitapide mesilate (JAN) D10385 Ezetimibe and atorvastatin D08488 Amlodipine besilate and atorvastatin calcium D00351 Ketoconazole (JP18/USP) DG00375 Terbinafine D02375 Terbinafine (USAN/INN) D02219 Terbinafine hydrochloride (JP18/USP) D09544 Ozenoxacin (JAN/USAN/INN) DG00410 Methylprednisolone D00407 Methylprednisolone (JP18/USP/INN) D00751 Methylprednisolone sodium succinate (JAN/USP) D00979 Methylprednisolone acetate (JAN/USP) D05000 Methylprednisolone hemisuccinate (USP); Methylprednisolone succinate (JP18) D05001 Methylprednisolone sodium phosphate (USAN) D05002 Methylprednisolone suleptanate (USAN/INN) D07203 Methylprednisolone aceponate (INN) DG00419 Mometasone D08227 Mometasone (INN) D00690 Mometasone furoate (JAN/USP) D03325 Mometasone furoate hydrate (JAN) DG00420 Fluticasone D07981 Fluticasone (INN) D01708 Fluticasone propionate (JAN/USP) D06315 Fluticasone furoate (JAN/USAN/INN) D00592 Dapsone (USP); Diaphenylsulfone (JAN) DG00439 Tacrolimus D08556 Tacrolimus (INN) D00107 Tacrolimus (USP/INN); Tacrolimus hydrate (JP18) DG00719 Ruxolitinib D09959 Ruxolitinib (USAN/INN) D09960 Ruxolitinib phosphate (JAN/USAN) D00321 Finasteride (JAN/USP/INN) D00804 Ivermectin (JAN/USP/INN) DG00974 Caffeine D00528 Caffeine (USP); Anhydrous caffeine (JP18) D01453 Caffeine hydrate (JP18) D07603 Caffeine citrate (USP) DG00445 Methylergometrine D08207 Methylergometrine (INN) D00680 Methylergonovine maleate (USP); Methylergometrine maleate (JP18) DG00446 Ergometrine D07905 Ergometrine (INN) D01163 Ergonovine maleate (USP); Ergometrine maleate (JP18) DG00452 Bromocriptine D03165 Bromocriptine (USAN/INN) D00780 Bromocriptine mesylate (USP); Bromocriptine mesilate (JP18) D00987 Cabergoline (JP18/USP/INN) D02577 Flibanserin (USAN/INN) D04463 Norgestrel and ethinylestradiol tablets (JP18) D09741 Drospirenone and ethinylestradiol D03917 Drospirenone (JAN/USP/INN) DG00461 Ethinylestradiol D00554 Ethinyl estradiol (USP); Ethinylestradiol (JP18/INN) D07928 Ethinylestradiol propanesulfonate DG00462 Estradiol D00105 Estradiol (JAN/USP/INN) D01413 Estradiol valerate (JAN/USP/INN) D01617 Estradiol dipropionate (JAN) D01953 Estradiol benzoate (JP18/USP) D04061 Estradiol acetate (USAN) D04063 Estradiol cypionate (USP) D04064 Estradiol enanthate (USAN) D04065 Estradiol undecylate (USAN/INN) D07918 Estradiol hemihydrate D07919 Estradiol 17 beta-hemisuccinate DG00464 Estrone D00067 Estrone (JAN/USP/INN) D00312 Estrone sodium sulfate D00948 Estropipate (USP) DG00465 Conjugated estrogen D04070 Estrogens, conjugated (JAN/USP) D05987 Synthetic conjugated estrogens, B (USAN) D00066 Progesterone (JP18/USP/INN) D01217 Dydrogesterone (JP18/USP/INN) D03799 Dienogest (JAN/USAN/INN) D09188 Estradiol and norethindrone D09187 Estradiol and levonorgestrel D00585 Mifepristone (JAN/USAN/INN) DG00478 Oxybutynin D00465 Oxybutynin (USAN/INN) D00722 Oxybutynin chloride (USP); Oxybutynin hydrochloride (JP18) DG00479 Propiverine D08441 Propiverine (INN) D01007 Propiverine hydrochloride (JP18) DG00480 Tolterodine D00646 Tolterodine (USAN/INN) D01148 Tolterodine tartrate (JAN/USP) DG00481 Solifenacin D08522 Solifenacin (INN) D01269 Solifenacin succinate (JAN/USAN/INN) DG00482 Darifenacin D03654 Darifenacin (USAN/INN) D01699 Darifenacin hydrobromide (JAN/USAN) DG00483 Fesoterodine D07226 Fesoterodine (INN) D08923 Fesoterodine fumarate (JAN/USAN) D09535 Mirabegron (JAN/USAN/INN) D06273 Imidafenacin (JAN/INN) DG00484 Sildenafil D08514 Sildenafil (INN) D02229 Sildenafil citrate (JAN/USP) D02008 Tadalafil (JAN/USP/INN) DG00487 Vardenafil D08668 Vardenafil (USAN/INN) D02731 Vardenafil dihydrochoride (USAN) D03260 Vardenafil hydrochloride hydrate (JAN) D09989 Vardenafil hydrochloride (USP) D03217 Avanafil (USAN/INN) DG00489 Alfuzosin D07124 Alfuzosin (INN) D01692 Alfuzosin hydrochloride (JAN/USAN) D01965 Silodosin (JP18/INN) D11389 Dutasteride and tamsulosin D03820 Dutasteride (JAN/USP/INN) D12486 Finasteride and tadalafil D03671 Deflazacort (USAN/INN) DG02839 Osilodrostat D11061 Osilodrostat (USAN/INN) D11062 Osilodrostat phosphate (JAN/USAN) DG00513 Cinacalcet D03504 Cinacalcet (USAN) D03505 Cinacalcet hydrochloride (JAN/USAN) D01322 Troleandomycin (USAN/INN); Triacetyloleandomycin (JAN) DG00605 Clarithromycin D00276 Clarithromycin (JP18/USP/INN) D07710 Clarithromycin lactobionate DG00616 Ofloxacin D00453 Ofloxacin (JP18/USP/INN) D08291 Ofloxacin hydrochloride DG03066 Lefamulin D11631 Lefamulin (USAN/INN) D11632 Lefamulin acetate (USAN) D00350 Itraconazole (JP18/USP) D00424 Rifabutin (JAN/USP/INN) DG00644 Bedaquiline D09872 Bedaquiline (USAN/INN) D09873 Bedaquiline fumarate (JAN/USAN) D09785 Delamanid (JAN/USAN) DG00653 Saquinavir D00429 Saquinavir (JAN/USP/INN) D01160 Saquinavir mesylate (USP); Saquinavir mesilate (JAN) DG00654 Indinavir C07051 Indinavir D03833 Indinavir (USAN) D00897 Indinavir sulfate (USP) D02861 Indinavir sulfate ethanolate (JAN) DG00655 Nelfinavir D08259 Nelfinavir (INN) D00899 Nelfinavir mesylate (USAN/INN); Nelfinavir mesilate (JAN) D00894 Amprenavir (JAN/USAN/INN) DG00656 Fosamprenavir D02497 Fosamprenavir (INN) D02867 Fosamprenavir calcium hydrate (JAN) D03835 Fosamprenavir calcium (USAN) D03837 Fosamprenavir sodium (USAN) DG00659 Darunavir D03656 Darunavir (USAN/INN) D06478 Darunavir ethanolate (JAN) D12637 Darunavir hydrate D12269 Nirmatrelvir and ritonavir D00435 Nevirapine (JAN/USP/INN) D00896 Efavirenz (JAN/USP/INN) D04112 Etravirine (JAN/USAN/INN) DG00667 Dolutegravir D10066 Dolutegravir (USAN) D10113 Dolutegravir sodium (JAN/USAN) D09012 Telaprevir (JAN/USAN/INN) DG01669 Daclatasvir D10065 Daclatasvir (USAN) D10105 Daclatasvir dihydrochloride (USAN); Daclatasvir hydrochloride (JAN) D10745 Ombitasvir, paritaprevir and ritonavir D10827 Sofosbuvir and velpatasvir D10600 Dolutegravir, abacavir and lamivudine D10753 Atazanavir and cobicistat D06670 Maraviroc (JAN/INN) D04859 Maribavir (JAN/USAN/INN) DG00675 Cyclophosphamide D07760 Cyclophosphamide (INN) D00287 Cyclophosphamide (USP); Cyclophosphamide hydrate (JP18) D00343 Ifosfamide (JAN/USP/INN) DG00689 Vinblastine D08675 Vinblastine (INN) D01068 Vinblastine sulfate (JP18/USP) DG00692 Vinorelbine D08680 Vinorelbine (INN) D01935 Vinorelbine tartrate (USP); Vinorelbine ditartrate (JAN) DG00694 Docetaxel D07866 Docetaxel (JAN/INN) D02165 Docetaxel (USP); Docetaxel hydrate (JP18) DG00726 Irinotecan D08086 Irinotecan (INN) D01061 Irinotecan hydrochloride (USP); Irinotecan hydrochloride hydrate (JP18) D10642 Irinotecan sucrosofate (USAN) D06199 Trabectedin (JAN/USAN/INN) D04645 Ixabepilone (JAN/USAN/INN) DG00710 Imatinib D08066 Imatinib (INN) D01441 Imatinib mesylate (USAN); Imatinib mesilate (JAN) DG00714 Dasatinib D03658 Dasatinib (JAN/INN) D06414 Dasatinib (USAN); Dasatinib hydrate (JAN) D12609 Dasatinib laurylsulfate (USAN) DG00716 Nilotinib D08953 Nilotinib (USAN/INN) D06413 Nilotinib hydrochloride hydrate (JAN) D12444 Nilotinib hydrochloride dihydrate (JAN) DG00718 Bosutinib D03252 Bosutinib (USAN) D09728 Bosutinib hydrate (JAN) DG03004 Asciminib D11403 Asciminib (USAN/INN) D11404 Asciminib hydrochloride (JAN/USAN) DG00711 Erlotinib D07907 Erlotinib (INN) D04023 Erlotinib hydrochloride (JAN/USAN) DG00721 Dabrafenib D10064 Dabrafenib (USAN) D10104 Dabrafenib mesylate (USAN); Dabrafenib mesilate (JAN) D11053 Encorafenib (JAN/USAN/INN) D09731 Crizotinib (JAN/USAN/INN) DG01625 Alectinib D10542 Alectinib (USAN/INN) D10450 Alectinib hydrochloride (JAN) D10866 Brigatinib (JAN/USAN) DG01414 Selumetinib D09666 Selumetinib (USAN/INN) D10024 Selumetinib sulfate (JAN/USAN) DG02084 Ribociclib D10883 Ribociclib (USAN/INN) D10979 Ribociclib succinate (USAN) D06068 Temsirolimus (JAN/USAN/INN) D02714 Everolimus (JAN/USAN/INN) D00753 Sirolimus (JAN/USAN/INN) DG00715 Lapatinib D08108 Lapatinib (INN) D04024 Lapatinib ditosylate (USAN); Lapatinib tosilate hydrate (JAN) DG02968 Fedratinib D10630 Fedratinib (USAN/INN) D11296 Fedratinib hydrochloride (USAN); Fedratinib hydrochloride hydrate (JAN) D11768 Pacritinib (USAN/INN) D03218 Axitinib (JAN/USAN) DG01375 Tivozanib D09683 Tivozanib (USAN/INN) D10190 Tivozanib hydrochloride (USAN) D10927 Erdafitinib (JAN/USAN/INN) D11417 Pemigatinib (JAN/USAN/INN) DG00712 Sunitinib D08552 Sunitinib (INN) D06402 Sunitinib malate (JAN/USAN) D06407 Vandetanib (JAN/USAN/INN) DG00720 Regorafenib D10138 Regorafenib (USAN/INN) D10137 Regorafenib hydrate (JAN) D05029 Midostaurin (JAN/USAN/INN) DG01948 Gilteritinib D10709 Gilteritinib (USAN/INN) D10800 Gilteritinib fumarate (JAN/USAN) D10926 Entrectinib (JAN/USAN/INN) DG02960 Pexidartinib D11270 Pexidartinib (USAN/INN) D11271 Pexidartinib hydrochloride (JAN/USAN) DG02081 Capmatinib D10696 Capmatinib (USAN/INN) D10891 Capmatinib hydrochloride (USAN); Capmatinib hydrochloride hydrate (JAN) DG03087 Tepotinib D11717 Tepotinib (USAN/INN) D11073 Tepotinib hydrochloride (USAN); Tepotinib hydrochloride hydrate (JAN) D11713 Selpercatinib (JAN/USAN/INN) D03259 Gemtuzumab ozogamicin (USAN); Gemtuzumab ozogamicin (genetical recombination) (JAN); Gemtuzumab (INN) DG01403 Panobinostat D10319 Panobinostat (USAN/INN) D10019 Panobinostat lactate (JAN) D08870 Belinostat (USAN/INN) D08914 Eribulin mesylate (USAN); Eribulin mesilate (JAN) D11222 Selinexor (USAN/INN) D11954 Belzutifan (JAN/USAN/INN) D12301 Adagrasib (USAN/INN) DG00734 Tamoxifen D08559 Tamoxifen (INN) D00966 Tamoxifen citrate (JP18/USP) |